cast
-
Adrien Brody
Psycho Ed
-
Matt Bush
Henry Burke
-
Sean Marquette
Travis Breaux
-
Colin Hanks
Brandon Ellis
-
Michael Chiklis
Dr. Leslie Gordon
-
Adhir Kalyan
Sebastian Saleem
-
Mykelti Williamson
Paranoid
-
Luis Chávez
Big Dave
-
Max Van Ville
Little Dave
-
Brett Kelly
Martin Gordon
-
George Back
Malcolm
-
Alicia Sixtos
Sharky Ovante
-
Andrew Wilson
Hippie Dude
-
Camille Mana
Dana
-
Erica Vittina Phillips
Tameka
- Arcadiy Golubovich Edwin Hunter
-
Julia Ling
Charlyne
-
Cody Longo
Chad
-
Mary Birdsong
Mrs. Gordon
-
Yeardley Smith
Computer Skills Teacher
-
Curtis Armstrong
Mr. Thompson
- Alex Biats Spelling Bee Rival
- John Beard Male News Desk Reporter
-
Barret Swatek
Female News Desk Reporter
-
Rhys Coiro
Vato
-
Wyatt Russell
Drug PSA Stoned Teenager
-
Mike Eshaq
Lead Terrorist
- Heather Elizabeth Regan Cheerleader who collides with Henry
- Terri Lyn Rodriguez Vivian
-
Robert Bailey Jr.
Jeffrey
- Kelli Rasmus Hippie Chick
- Shirley Benyas Older Female Donor
-
Wallace Bridges
African American Donor
- Carl Harry Carlson Donor #1
- Randy Godwin Donor #2
- Mike Evans Donor #3
-
Linda Boston
Head Nurse
-
Nadine Crocker
Emily Tooms
- Clarence Smith Chess Opponent
- Ron Ayers Stunned Lawn Bowler
- Karl Murphy Band Teacher
-
Rachel Quaintance
Angry Parent #1
-
Peter Tocco
Angry Parent #2
- Mike Woods Announcer
- Kerry Birmingham Female Reporter
- Kevin Yon Mr. Cavanaugh
-
Sammy A. Publes
Cook #1
- Rene Santana Cook #2
- Billye Thompson Cop #1
-
J. J. Soria
Rubin
- David Herbst School Security Guard
-
John O'Hurley
Drug PSA (voice)
-
John Stalberg Jr.
Grandpa Frodo - Ed's Frog (voice)
- Heather Kleisner Henry's Mom (voice)
- D.B. Dickerson Stoned High School Student (uncredited)
- Sabrina Dungan High School Student (uncredited)
- Penny Gibbs School Admin (uncredited)
- Adam Lorenz Dwayne Reynolds (uncredited)
- Bill Lumbert Concerned Parent (uncredited)
- Misty Mills Teacher (uncredited)
- Jerry Reid High School Student (uncredited)
- Steven Sutherland Academy Student (uncredited)
- Joe Tinpan Terrorist (uncredited)
-
Michael Vartan
Calculus Teacher (uncredited)
-
Amanda Bright
High School Student (uncredited)
- Kathi J. Moore Librarian