cast
-
Neil deGrasse Tyson
Self - Host
-
Ann Druyan
-
Carl Sagan
Self (archive footage) / Self (voice) (archive footage)
-
Seth MacFarlane
Giordano Bruno (voice) / President Harry S. Truman (voice) / Sherwood Rowland (voice) / (voice)
-
Sasha Sagan
Rachel Molly Gruber
-
Stoney Emshwiller
Guard (voice)
-
André Sogliuzzo
Christopher Wren (voice) / Weichelberger (voice)
-
Christopher Emerson
Acolyte (voice)
-
Piotr Michael
Edmund Muskie (voice) / Lab Assistant (voice)
-
Enn Reitel
Henry Norris Russell (voice)
-
Keythe Farley
(voice)
-
Patrick Stewart
William Herschel (voice)
-
Elizardo Torrez
Young Carl Sagan
-
Trang Vo
(voice) / Birthmark Woman
-
John Steven Rocha
Bellaramine (voice)
-
Paul Telfer
Angry Scholar #2 (voice)
-
Jonathan Morgan Heit
John Herschel (voice)
-
Cary Elwes
Edmond Halley / Robert Hooke (voice)
-
Tom Konkle
Samuel Pepys (voice)
-
Alexander Siddig
Isaac Newton (voice)
-
Alfred Molina
Ibn al-Haytham (voice)
-
Richard Gere
Clair Patterson (voice)
-
Marc Worden
Harrison Brown (voice)
-
Kirsten Dunst
Cecilia Payne (voice)
-
Marlee Matlin
Annie Jump Cannon (voice)
-
Peggy Jo Jacobs
Margaret Harwood (voice)
-
Amanda Seyfried
Marie Tharp (voice)
-
Christiane Amanpour
Enheduanna (voice)
-
Michael Chochol
Jan Oort
-
Oliver Vaquer
Joseph von Fraunhofer (voice)
-
Fred Tatasciore
Democritus (voice)
-
Larry Cedar
-
Nick Jameson
-
Michael McConnohie
-
Masasa Moyo
- Maria Frucci
-
Martin Jarvis
Humphry Davy (voice)
-
Noah Langford
(voice)
-
Fay Masterson
(voice)
-
Heiko Obermöller
Einstein's Father (voice)
-
Julian Ovenden
Michael Faraday (voice)
- Jack Rainsford (voice)
-
Glenn Steinbaum
Bruce Heezen (voice)
-
William Salyers
(voice)
-
Paul Sorvino
Augustin Mouchot (voice)
-
Eliza Schneider
(voice)
-
Frank Baxter
Self (archive footage)
-
John F. Kennedy
Self (voice) (archive footage)
- Masoumeh Husseini Monk (voice)
-
Harssh A. Singh
Ashoka (voice)
-
Nick Sagan
-
Clinnette Minnis
-
Shereen Balles
Female Voyager (voice)
-
Kapeneta Te'o-Tafiti
Male Voyager (voice)
- Joseph Grange John Herschel (voice)
-
Carol Bach Rita
Caroline Herschel (voice)
-
Viggo Mortensen
Nikolai Vavilov (voice)
-
Ken Lally
(voice)
-
Phil Crowley
(voice)
-
Yuri Lowenthal
(voice)
-
Edita Brychta
(voice)
-
Christopher Lee Parson
(voice)
-
Andrew Pifko
(voice)
-
Brendan Bradley
(voice)
-
Matthew Jayson Cwern
(voice)
-
Alan Shearman
(voice)
-
Natasha Goubskaya
(voice)
- Skye Sammoutis (voice)
-
Marcelo Tubert
(voice)
-
Mara Junot
(voice)
-
Rick Pasqualone
(voice)
-
Elijah Braik
(voice)
-
Novi Brown
(voice)
-
Jamie Hanes
-
Will Greenburg
John Goodricke
- Dex de Groot
- Joep Fellinger
-
Steve Oatway
Charles Darwin
-
Adam Tsekhman
Christiaan Huygens
-
Neil Arnote
Neil Armstrong
-
Ernie Vigil
Thomas Young
-
Judd Hirsch
Robert Oppenheimer (voice)
-
Olivia D'Abo
Marie Curie (voice)
- Yurika Okamura (voice)
- Selyna Chan (voice)
- Sianna Chan (voice)
-
Joseph J. Micucci
Young Father
-
Lennard Ortmann
Albert Einstein
-
Alex Bartram
Samuel Sagan
-
Brannon Braga
World's Fair Attendee
-
Marcello Guedes
Young Neil deGrasse Tyson
-
Leandro Guedes
Young Stephen Joseph Tyson
