cast
- Zac Jones Narrator (voice)
- Sami Jarroush Self - Historian
- Jack Riley Self - Former Principal Deputy Administrator, DEA
- Steve Cook Self - Motorcycle Gang Investigator, Independence PD Detective
- Kerrie Droban Self - Author, 'Running With the Devil' / Self - Author, 'Vagos, Mongols & Outlaws'
- Anthony M. DeStefano Self - Author, 'Gotti's Boys'
- John Gotti Self - Boss of the Gambino Crime Family (archive footage)
- Carlo Gambino Self - Boss of the Gambino Crime Family (archive footage)
- Albert Anastasia Self - Boss of the Gambino Crime Family (archive footage)
- Paul Castellano Self - Boss of the Gambino Crime Family (archive footage)
- Sammy 'The Bull' Gravano Self - Underboss of the Gambino Crime Family (archive footage)
- Thomas Bilotti Self - Underboss of the Gambino Crime Family (archive footage)
- Aniello 'Neil' Dellacroce Self - Underboss of the Gambino Crime Family (archive footage)
- Anthony 'Nino' Gaggi Self - Caporegime in the Gambino Crime Family (archive footage)
- Joseph Armone Self - Caporegime in the Gambino Crime Family (archive footage)
- James Failla Self - Caporegime in the Gambino Crime Family (archive footage)
- Joseph N. Gallo Self - Consigliere of the Gambino Crime Family (archive footage)
- Frank Locascio Self - Consigliere of the Gambino Crime Family (archive footage)
- Louis DiBono Self - Soldier in the Gambino Crime Family (archive footage)
- Angelo Ruggiero Self - Soldier in the Gambino Crime Family (archive footage)
- Gene Gotti Self - Soldier in the Gambino Crime Family (archive footage)
-
Al Capone
Self - Boss of the Chicago Outfit (archive footage)
- Drew Hogan Self - DEA Special Agent, Ret. / Author, 'Hunting El Chapo'
- Noah Hurowitz Self - Author, 'El Chapo: The Untold Story of the World's Most Infamous Drug Lord'
- Steve Murphy Self - DEA Special Agent, Ret. / Co-Author, 'Manhunt: How We Took Down Pablo Escobar'
- Javier Peña Self - DEA Special Agent, Ret. / Co-Author, 'Manhunt: How We Took Down Pablo Escobar'
- Ray Donovan Self - Former Chief of Operations, DEA
- Joaquín 'El Chapo' Guzmán Self - Leader of the Sinaloa Cartel (archive footage)
- Héctor Salazar Self - Leader of the Sinaloa Cartel (archive footage)
- Ismael 'El Mayo' Zambada Self - Leader of the Sinaloa Cartel (archive footage)
- Benjamín Arellano Félix Self - Leader of the Tijuana Cartel (archive footage)
- Ramón Arellano Félix Self - Leader of the Tijuana Cartel (archive footage)
- Aldona Bialowas Pobutsky Self - Associate Professor, Oakland University / Author, 'Pablo Escobar and Colombian Narcoculture'
- Julian Sher Self - Author, 'Angels of Death'
- Joel Selvin Self - Author, 'Altamont'
- Sonny Barger Self - President of the Hells Angels (archive footage)
- David 'Lil Dave' Santillan Self - Former International President, Mongols MC
- Justin 'Mooch' DeLoretto Self - Former Mongols MC Member / Author, 'Ride of My Life'
- Billy Queen Self - ATF Special Agent, Ret. / Author, 'Under and Alone'
- Ruben 'Doc' Cavazos Self - International President of the Mongols MC (archive footage)
- Tom Foley Self - Colonel & Superintendent (Ret.), Massachusetts State Police
- Emily Sweeney Self - Boston Globe Journalist / Author, 'Gangland Boston'
- Phyllis Karas Self - Adjunct Professor, BU School of Journalism / Co-Author, 'Brutal'
- Geoff Schumacher Self - VP of Exhibits & Programs, The Mob Museum
-
James 'Whitey' Bulger
Self - Boss of the Winter Hill Gang (archive footage)
- Howie Winter Self - Boss of the Winter Hill Gang (archive footage)
-
Pablo Escobar
Self - Boss of the Medellin Cartel (archive footage)
- José Rodriguez Gacha Self - Leader of the Medellin Cartel (archive footage)
- Gustavo Gaviria Self - Leader of the Medellin Cartel (archive footage)
- Fabio Ochoa Self - Leader of the Medellin Cartel (archive footage)
- Jorge Ochoa Self - Leader of the Medellin Cartel (archive footage)
- Juan David Ochoa Self - Leader of the Medellin Cartel (archive footage)
- Carlos Lehder Self - Medellin Cartel Pilot (archive footage)
- Stephen Flemmi Self - Lieutenant in the Winter Hill Gang (archive footage)
- Kevin Weeks Self - Lieutenant in the Winter Hill Gang (archive footage)
- Frankie Angiulo Self - New England Mafia (archive footage)
- Gennaro Angiulo Self - New England Mafia (archive footage)
- John Connolly Self - FBI Agent (archive footage)
- John McIntyre Self - FBI Informant (archive footage)
